Salvia Officinalis and Alzheimer's Disease
Salvia Officinalis (Sage)
Salvia Officinalis functions in a similar way as some prescriptions medicines used to treat Alzheimer's.
Studies have shown that supplementation with sage led to improved memory and better cognitive ability in individuals with Alzheimer's disease.
Salvia Officinalis & The Brain
Better known by its common name, sage, Salvia Officinalis has several benefits for mental health. Salvia Officinalis has been shown to reduce inflammation and act as an anti-oxidant. Inflammation and oxidants are both believed to be significant contributors to the damage seen in Alzheimer’s disease.
Salvia Officinalis inhibits cholinesterase. Cholinesterase is a harmful enzyme that contributes to the brain damage seen in Alzheimer’s disease. Several prescription medicines used to treat Alzheimer’s(donepezil/Aricept & rivastigmine/Exelon) are “cholinesterase inhibitors” and work in a similar fashion to Salvia Officinalis, attempting to inhibit cholinesterase.
The Evidence, Research & Studies
Six studies examined the effects of Salvia Officinalis supplementation on healthy individuals and each study found that Salvia Officinalis supplementation led to an increase in memory, mood, or both.
Two studies examined the effects Salvia Officinalis supplementation on individuals with potential cognitive problems. One study found that Salvia Officinalis supplementation led to a reduction in cognitive problems and an improvement in attention and the other study found that Salvia Officinalis supplementation led to “significantly better cognitive function.” [Sources 7 & 8]